SFF51903.1 protein (Thermoflexibacter ruber)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

SFF51903.1

RHS repeat-associated core domain-containing protein. (417 aa)

Predicted Functional Partners:

SFF17126.1

0.776

SFF57514.1

0.775

SFF61464.1

0.774

SFF51894.1

0.773

SFF57852.1

0.772

SFF65576.1

0.772

SFF61846.1

0.770

SFF54204.1

0.765

SFF51915.1

0.762

SFF56165.1

0.752

Your Current Organism:

Thermoflexibacter ruber

NCBI taxonomy Id: 1003
Other names: ATCC 23103, DSM 9560, Flexibacter ruber, IFO 16677, LMG 13857, LMG:13857, NBRC 16677, T. ruber, strain GEY

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SFF17126.1	SFF51903.1	SAMN04488541_101898	SAMN04488541_104626	Hypothetical protein.	RHS repeat-associated core domain-containing protein.	0.776
SFF17126.1	SFF54204.1	SAMN04488541_101898	SAMN04488541_105212	Hypothetical protein.	Hypothetical protein.	0.750
SFF17126.1	SFF56165.1	SAMN04488541_101898	SAMN04488541_105815	Hypothetical protein.	YD repeat-containing protein.	0.695
SFF17126.1	SFF57514.1	SAMN04488541_101898	SAMN04488541_10638	Hypothetical protein.	Hypothetical protein.	0.835
SFF17126.1	SFF57852.1	SAMN04488541_101898	SAMN04488541_106513	Hypothetical protein.	RHS repeat-associated core domain-containing protein.	0.769
SFF17126.1	SFF61464.1	SAMN04488541_101898	SAMN04488541_10837	Hypothetical protein.	RHS repeat-associated core domain-containing protein.	0.773
SFF17126.1	SFF61846.1	SAMN04488541_101898	SAMN04488541_10856	Hypothetical protein.	Hypothetical protein.	0.717
SFF17126.1	SFF65576.1	SAMN04488541_101898	SAMN04488541_11231	Hypothetical protein.	RHS repeat-associated core domain-containing protein.	0.771
SFF51894.1	SFF51903.1	SAMN04488541_104625	SAMN04488541_104626	Hypothetical protein.	RHS repeat-associated core domain-containing protein.	0.773
SFF51894.1	SFF51915.1	SAMN04488541_104625	SAMN04488541_104627	Hypothetical protein.	Hypothetical protein.	0.762
SFF51903.1	SFF17126.1	SAMN04488541_104626	SAMN04488541_101898	RHS repeat-associated core domain-containing protein.	Hypothetical protein.	0.776
SFF51903.1	SFF51894.1	SAMN04488541_104626	SAMN04488541_104625	RHS repeat-associated core domain-containing protein.	Hypothetical protein.	0.773
SFF51903.1	SFF51915.1	SAMN04488541_104626	SAMN04488541_104627	RHS repeat-associated core domain-containing protein.	Hypothetical protein.	0.762
SFF51903.1	SFF54204.1	SAMN04488541_104626	SAMN04488541_105212	RHS repeat-associated core domain-containing protein.	Hypothetical protein.	0.765
SFF51903.1	SFF56165.1	SAMN04488541_104626	SAMN04488541_105815	RHS repeat-associated core domain-containing protein.	YD repeat-containing protein.	0.752
SFF51903.1	SFF57514.1	SAMN04488541_104626	SAMN04488541_10638	RHS repeat-associated core domain-containing protein.	Hypothetical protein.	0.775
SFF51903.1	SFF57852.1	SAMN04488541_104626	SAMN04488541_106513	RHS repeat-associated core domain-containing protein.	RHS repeat-associated core domain-containing protein.	0.772
SFF51903.1	SFF61464.1	SAMN04488541_104626	SAMN04488541_10837	RHS repeat-associated core domain-containing protein.	RHS repeat-associated core domain-containing protein.	0.774
SFF51903.1	SFF61846.1	SAMN04488541_104626	SAMN04488541_10856	RHS repeat-associated core domain-containing protein.	Hypothetical protein.	0.770
SFF51903.1	SFF65576.1	SAMN04488541_104626	SAMN04488541_11231	RHS repeat-associated core domain-containing protein.	RHS repeat-associated core domain-containing protein.	0.772

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

33

average node degree:

6

avg. local clustering coefficient:

0.906

expected number of edges:

29

PPI enrichment p-value:

0.282

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006508

Proteolysis

5 of 108

1.21

0.8

0.0098

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004252

Serine-type endopeptidase activity

5 of 35

1.7

1.96

2.74e-05

GO:0047617

acyl-CoA hydrolase activity

2 of 3

2.37

1.13

0.0082

GO:0016787

Hydrolase activity

8 of 654

0.63

0.45

0.0082

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1525

Mostly uncharacterized, incl. KR domain, and Trypsin-like peptidase domain

6 of 53

1.6

2.09

3.84e-06

CL:1583

Trypsin-like peptidase domain, and Antigen processing-Cross presentation

3 of 5

2.32

1.99

0.00017

CL:1528

Mixed, incl. Trypsin-like peptidase domain, and KR domain

5 of 38

1.66

1.93

2.66e-05

CL:2514

Mixed, incl. CoA hydrolase activity, and Lipoprotein

2 of 6

2.07

0.84

0.0263

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0042597

Periplasmic space

4 of 95

1.17

0.62

0.0324

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF13365

Trypsin-like peptidase domain

5 of 5

2.54

4.18

8.68e-09

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00228

Domain present in PSD-95, Dlg, and ZO-1/2.

3 of 5

2.32

2.08

0.00011

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