STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
acsAacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (668 aa)    
Predicted Functional Partners:
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
 
 0.987
AEW94202.1
Type II citrate synthase; Belongs to the citrate synthase family.
  
 0.968
AEW93234.1
Citrate synthase-like protein.
  
 0.957
AEW96603.1
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.956
AEW97148.1
Malate synthase; Belongs to the malate synthase family.
  
 0.954
AEW93232.1
Putative citrate synthase; Belongs to the citrate synthase family.
  
 0.952
AEW94756.1
Citrate synthase 2; Belongs to the citrate synthase family.
  
 0.952
AEW95865.1
Oxidoreductase.
  
 
 0.945
AEW93286.1
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.933
AEW93317.1
Aldehyde dehydrogenase; Catalyzes the oxidation of fluoroacetaldehyde to fluoroacetate. Has high affinity for fluoroacetate and glycolaldehyde but not for acetaldehyde.
  
 0.933
Your Current Organism:
Streptomyces cattleya
NCBI taxonomy Id: 1003195
Other names: S. cattleya NRRL 8057 = DSM 46488, Streptomyces cattleya DSM 46488, Streptomyces cattleya DSM 46488 = NRRL 8057, Streptomyces cattleya JCM 4925, Streptomyces cattleya NBRC 14057, Streptomyces cattleya NRRL 8057, Streptomyces cattleya NRRL 8057 = DSM 46488
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