STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEW95785.1Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (323 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.999
AEW95784.1
uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase.
 
 
 0.998
hemL
Glutamate-1-semialdehyde aminotransferase.
 
 
 0.997
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.988
AEW97639.1
uroporphyrin-III C-methyltransferase.
 
  
 0.927
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.841
rex
Redox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
       0.811
AEW93418.1
Precorrin-4 C11-methyltransferase.
 
   
 0.672
AEW93419.1
Precorrin methylase.
 
   
 0.652
AEW97052.1
Putative oxidoreductase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
 
  
 0.647
Your Current Organism:
Streptomyces cattleya
NCBI taxonomy Id: 1003195
Other names: S. cattleya NRRL 8057 = DSM 46488, Streptomyces cattleya DSM 46488, Streptomyces cattleya DSM 46488 = NRRL 8057, Streptomyces cattleya JCM 4925, Streptomyces cattleya NBRC 14057, Streptomyces cattleya NRRL 8057, Streptomyces cattleya NRRL 8057 = DSM 46488
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