| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| F2 | F7 | ENSMAUP00000007879 | ENSMAUP00000009870 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Coagulation factor VII. | 0.921 |
| F2 | Plat | ENSMAUP00000007879 | ENSMAUP00000016988 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Plasminogen activator; Belongs to the peptidase S1 family. | 0.513 |
| F2 | Plau | ENSMAUP00000007879 | ENSMAUP00000003122 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Urokinase-type plasminogen activator. | 0.418 |
| F2 | Plg | ENSMAUP00000007879 | ENSMAUP00000003135 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | 0.942 |
| F2 | Proc | ENSMAUP00000007879 | ENSMAUP00000002547 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Vitamin K-dependent protein C isoform X2. | 0.993 |
| F2 | Proz | ENSMAUP00000007879 | ENSMAUP00000025865 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Vitamin K-dependent protein Z isoform X1; Belongs to the peptidase S1 family. | 0.897 |
| F2 | Serpinb2 | ENSMAUP00000007879 | ENSMAUP00000000044 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Plasminogen activator inhibitor 2; Belongs to the serpin family. | 0.812 |
| F2 | Serpinb8 | ENSMAUP00000007879 | ENSMAUP00000000933 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Serpin B8; Belongs to the serpin family. | 0.769 |
| F2 | Serpine1 | ENSMAUP00000007879 | ENSMAUP00000002846 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Plasminogen activator inhibitor 1; Belongs to the serpin family. | 0.560 |
| F2 | Vtn | ENSMAUP00000007879 | ENSMAUP00000001926 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Vitronectin. | 0.774 |
| F7 | F2 | ENSMAUP00000009870 | ENSMAUP00000007879 | Coagulation factor VII. | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.921 |
| F7 | Plau | ENSMAUP00000009870 | ENSMAUP00000003122 | Coagulation factor VII. | Urokinase-type plasminogen activator. | 0.542 |
| F7 | Proc | ENSMAUP00000009870 | ENSMAUP00000002547 | Coagulation factor VII. | Vitamin K-dependent protein C isoform X2. | 0.766 |
| F7 | Serpinb2 | ENSMAUP00000009870 | ENSMAUP00000000044 | Coagulation factor VII. | Plasminogen activator inhibitor 2; Belongs to the serpin family. | 0.651 |
| F7 | Serpinb8 | ENSMAUP00000009870 | ENSMAUP00000000933 | Coagulation factor VII. | Serpin B8; Belongs to the serpin family. | 0.638 |
| F7 | Serpine1 | ENSMAUP00000009870 | ENSMAUP00000002846 | Coagulation factor VII. | Plasminogen activator inhibitor 1; Belongs to the serpin family. | 0.527 |
| Plat | F2 | ENSMAUP00000016988 | ENSMAUP00000007879 | Plasminogen activator; Belongs to the peptidase S1 family. | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.513 |
| Plat | Plg | ENSMAUP00000016988 | ENSMAUP00000003135 | Plasminogen activator; Belongs to the peptidase S1 family. | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | 0.945 |
| Plat | Serpinb2 | ENSMAUP00000016988 | ENSMAUP00000000044 | Plasminogen activator; Belongs to the peptidase S1 family. | Plasminogen activator inhibitor 2; Belongs to the serpin family. | 0.934 |
| Plat | Serpinb8 | ENSMAUP00000016988 | ENSMAUP00000000933 | Plasminogen activator; Belongs to the peptidase S1 family. | Serpin B8; Belongs to the serpin family. | 0.537 |