Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Gpr183G-protein coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (357 aa)    
Predicted Functional Partners:
Eif2b1
Translation initiation factor eIF-2B subunit alpha; Belongs to the eIF-2B alpha/beta/delta subunits family.
    
   0.859
Gnai1
Guanine nucleotide-binding protein G(I) subunit alpha-1.
    
  0.836
Gnai3
Guanine nucleotide-binding protein G(K) subunit alpha.
    
  0.836
Eif2b2
Translation initiation factor eIF-2B subunit beta isoform X1; Belongs to the eIF-2B alpha/beta/delta subunits family.
    
   0.787
Gng2
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
   0.786
Gpc6
Glypican-6 isoform X2; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
    
   0.761
Gnai2
Guanine nucleotide-binding protein G(I) subunit alpha-2.
    
 0.731
Hsd3b7
3 beta-hydroxysteroid dehydrogenase type 7 isoform X1; Belongs to the 3-beta-HSD family.
      
 0.723
Paxip1
PAX-interacting protein 1 isoform X1.
      
 0.700
Lime1
Lck-interacting transmembrane adapter 1 isoform X2.
      
 0.692
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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