Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ank1Ankyrin-1 isoform X17. (1907 aa)    
Predicted Functional Partners:
Sptb
Spectrin beta, erythrocytic.
   
 0.994
Spta1
Spectrin alpha chain, erythrocytic 1.
   
 0.991
Pikfyve
1-phosphatidylinositol 3-phosphate 5-kinase isoform X3.
    
   0.987
Slc4a1
Anion exchange protein.
   
 0.987
Fig4
Polyphosphoinositide phosphatase.
    
   0.983
Nfasc
Neurofascin.
   
 0.967
Cd44
CD44 antigen; Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment. Participates thereby in a wide variety of cellular functions including the activation, recirculation and homing of T-lymphocytes, hematopoiesis, inflammation and response to bacterial infection. Engages, through its ectodomain, extracellular matrix components such as hyaluronan/HA, collagen, growth factors, cytokines or proteases and serves as a platform for signal transduction by assembling, via its c [...]
     
 0.949
ENSMAUP00000001689
annotation not available
  
  
 
0.928
Tiam1
T-lymphoma invasion and metastasis-inducing protein 1.
    
 0.922
Itpr1
Inositol 1,4,5-trisphosphate receptor type 1 isoform X2.
    
 0.921
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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