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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ddx11ATP-dependent DNA helicase DDX11. (885 aa)    
Predicted Functional Partners:
Wrn
Werner syndrome ATP-dependent helicase isoform X1.
  
 0.991
Sympk
Symplekin.
    
   0.986
Ercc3
TFIIH basal transcription factor complex helicase XPB subunit.
   
 0.963
Gtf2h2
General transcription factor IIH subunit.
    
 0.960
Gtf2h3
General transcription factor IIH subunit 3.
    
 0.959
Gtf2h4
General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.
    
 0.958
Ccnh
cyclin-H; Belongs to the cyclin family.
    
 0.956
Mnat1
CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.
    
 0.956
Gtf2e1
General transcription factor IIE subunit 1.
   
 0.953
Chtf18
Chromosome transmission fidelity protein 18 homolog.
   
 
 0.950
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.