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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swi5LOW QUALITY PROTEIN: DNA repair protein SWI5 homolog. (110 aa)    
Predicted Functional Partners:
Tmem208
Transmembrane protein 208.
   
 
 0.983
Dmc1
Meiotic recombination protein DMC1/LIM15 homolog; Belongs to the RecA family.
    
 
 0.826
Rad51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
    
 
 0.822
Xrcc3
DNA repair protein XRCC3 isoform X3.
    
 
 0.817
Rad51c
DNA repair protein RAD51 homolog 3 isoform X1.
    
 
 0.734
Rad51b
DNA repair protein RAD51 homolog 2 isoform X2.
    
 
 0.715
Rad51d
DNA repair protein RAD51 homolog 4 isoform X2.
    
 
 0.715
Spo11
Meiotic recombination protein SPO11 isoform X1.
    
 
 0.679
Mnd1
Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family.
   
  
 0.604
Rad52
DNA repair protein RAD52 homolog isoform X3.
      
 0.503
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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