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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Fnip2Folliculin-interacting protein 2 isoform X2. (1144 aa)    
Predicted Functional Partners:
Flcn
Folliculin.
    
 0.999
Rragc
Ras-related GTP-binding protein C.
    
 0.989
Rraga
Ras-related GTP-binding protein A.
    
 0.973
Rragd
Ras-related GTP-binding protein D isoform X1.
    
 0.960
Lamtor4
Ragulator complex protein LAMTOR4 isoform X1.
    
 0.954
Fnip1
Folliculin-interacting protein 1 isoform X1.
  
0.950
Lamtor3
Ragulator complex protein LAMTOR3.
    
 0.923
Il4
Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...]
    
 0.915
Lamtor5
LOW QUALITY PROTEIN: ragulator complex protein LAMTOR5-like.
    
 0.913
LOC106021075
Ragulator complex protein LAMTOR5-like.
    
 0.913
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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