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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mlh3DNA mismatch repair protein Mlh3 isoform X3. (222 aa)    
Predicted Functional Partners:
Mlh1
DNA mismatch repair protein Mlh1.
    
 0.999
Msh2
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
 0.966
LOC106021697
DNA mismatch repair protein Msh6.
  
 0.949
Msh4
mutS protein homolog 4.
  
 0.949
Msh5
mutS protein homolog 5.
  
 0.949
Msh3
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
 0.949
Vta1
Vacuolar protein sorting-associated protein VTA1 homolog.
    
   0.934
Exo1
Exonuclease 1 isoform X1.
    
 0.888
Pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.875
Fan1
Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.
   
 0.856
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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