Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Pbx4pre-B-cell leukemia transcription factor 4 isoform X5. (380 aa)    
Predicted Functional Partners:
Pknox1
Homeobox protein PKNOX1 isoform X1.
    
 0.964
Hoxb1
Homeobox protein Hox-B1.
    
 0.949
Pknox2
Homeobox protein PKNOX2.
    
 0.923
Hoxa9
Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.
    
 
 0.914
Meis1
Homeobox protein Meis1 isoform X1.
   
 0.901
Meis2
Homeobox protein Meis2 isoform X3.
   
 0.901
Hoxb6
Homeobox protein Hox-B6.
    
 0.884
Hoxc4
Homeobox protein Hox-C4.
    
 0.880
Lmx1b
LIM homeobox transcription factor 1-beta; Essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels. Mediates physical interaction and transcriptional synergy with E47/PAN-1.
    
 
 0.880
Mab21l1
Putative nucleotidyltransferase MAB21L1.
    
 
 0.865
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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