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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Adgrf5Adhesion G protein-coupled receptor F5. (871 aa)    
Predicted Functional Partners:
Ptprb
Receptor-type tyrosine-protein phosphatase beta isoform X3.
   
 
 0.793
Cdh5
Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins.
   
  
 0.763
Sftpc
Pulmonary surfactant-associated protein C.
   
 
 0.750
Sspo
SCO-spondin isoform X1.
   
 
 0.731
Sftpb
Pulmonary surfactant-associated protein B isoform X1.
   
 
  0.667
Robo4
Roundabout homolog 4.
   
  
 0.606
Emcn
Endomucin isoform X2.
   
  
 0.589
Mmrn2
Multimerin-2.
   
 
 0.557
Afap1l1
GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
   
    0.532
Kdr
Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
    0.526
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.