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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GphnMolybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (708 aa)    
Predicted Functional Partners:
Glrb
Glycine receptor subunit beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
    
 
 0.990
Mocs1
Molybdenum cofactor biosynthesis protein 1 isoform X1.
 
 0.966
Mocos
Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
  
 
 0.951
Gabrg2
Gamma-aminobutyric acid receptor subunit gamma-2; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
    
 0.940
Mocs2
Molybdopterin synthase sulfur carrier subunit; Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin; Belongs to the MoaD family. MOCS2A subfamily.
     
 0.928
Gabra1
Gamma-aminobutyric acid receptor subunit alpha-1 isoform X2; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
    
 0.923
Gabra2
Gamma-aminobutyric acid receptor subunit alpha-2; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
    
 0.916
Gabrg1
Gamma-aminobutyric acid receptor subunit gamma-1; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
    
 0.916
Gabrg3
Gamma-aminobutyric acid receptor subunit gamma-3.
    
 0.911
Gabra5
Gamma-aminobutyric acid receptor subunit alpha-5; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
    
 0.905
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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