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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pdcd1Programmed cell death protein 1. (288 aa)    
Predicted Functional Partners:
Pdcd1lg2
Programmed cell death 1 ligand 2 isoform X2.
   
 0.998
Cd274
Programmed cell death 1 ligand 1 isoform X1.
  
 0.996
Ptpn11
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
    
 0.960
ENSMAUP00000013047
annotation not available
    
 0.931
Cd4
T-cell surface glycoprotein CD4.
   
 0.811
Cd80
T-lymphocyte activation antigen CD80 isoform X1.
    
 0.794
Lag3
Lymphocyte activation gene 3 protein.
   
 0.784
ENSMAUP00000017584
annotation not available
    
  0.784
Ctla4
Cytotoxic T-lymphocyte protein 4 isoform X1.
   
  
 0.784
Cd3d
T-cell surface glycoprotein CD3 delta chain precursor.
   
 
 0.725
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.