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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ctnna2Catenin alpha-2 isoform X1. (965 aa)    
Predicted Functional Partners:
Ctnnb1
Catenin beta-1.
   
 0.980
Vcl
Vinculin isoform X1.
    
0.968
Cdh1
Cadherin-1 isoform X1; Cadherins are calcium-dependent cell adhesion proteins.
    
 0.938
Jup
Junction plakoglobin.
   
 0.919
Ctnnd1
Catenin delta-1 isoform X7.
   
 0.877
Actn4
Actinin alpha 4.
   
 0.871
Tjp1
Tight junction protein ZO-1 isoform X8; Belongs to the MAGUK family.
    
 0.858
Actb
Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.
    
 0.842
Arvcf
Armadillo repeat protein deleted in velo-cardio-facial syndrome isoform X1.
   
 0.837
Actg1
Actin gamma 1.
    
 0.832
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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