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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pycr1Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (310 aa)    
Predicted Functional Partners:
Pycr2
Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.
  
 
0.966
Pycr3
Pyrroline-5-carboxylate reductase 3.
  
 
 
0.963
Aldh18a1
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
  
 
 0.915
Aldh4a1
Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.912
Prodh
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
   
 0.907
Prodh2
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
   
 0.907
Lap3
Cytosol aminopeptidase.
    
  0.848
P4ha2
Prolyl 4-hydroxylase subunit alpha-2.
     
 0.844
L3hypdh
trans-3-hydroxy-L-proline dehydratase isoform X2.
    
 0.832
Nudt5
ADP-sugar pyrophosphatase; Belongs to the Nudix hydrolase family.
   
   0.785
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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