Il1f8 protein (Mesocricetus auratus) - STRING interaction network

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Score

Il1f8

Interleukin-1. (190 aa)

Predicted Functional Partners:

Il1rl2

0.954

Il1r1

0.937

Il36rn

0.897

Il1rap

0.895

Il18

0.832

Il1f10

0.706

Il1a

0.704

Il1rl1

0.686

Il1b

0.676

Il18r1

0.622

Your Current Organism:

Mesocricetus auratus

NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Il18	Il18r1	ENSMAUP00000013280	ENSMAUP00000020245	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	Interleukin-18 receptor 1.	0.985
Il18	Il1a	ENSMAUP00000013280	ENSMAUP00000020526	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	Interleukin-1; Belongs to the IL-1 family.	0.691
Il18	Il1b	ENSMAUP00000013280	ENSMAUP00000019099	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.774
Il18	Il1f10	ENSMAUP00000013280	ENSMAUP00000023502	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	Interleukin-1.	0.750
Il18	Il1f8	ENSMAUP00000013280	ENSMAUP00000001323	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	Interleukin-1.	0.832
Il18	Il1r1	ENSMAUP00000013280	ENSMAUP00000000598	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	Interleukin-1 receptor type 1.	0.624
Il18	Il1rl1	ENSMAUP00000013280	ENSMAUP00000013887	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	Interleukin-1 receptor-like 1.	0.795
Il18	Il1rl2	ENSMAUP00000013280	ENSMAUP00000015737	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	Interleukin-1 receptor-like 2.	0.541
Il18	Il36rn	ENSMAUP00000013280	ENSMAUP00000023686	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	Interleukin-1.	0.832
Il18r1	Il18	ENSMAUP00000020245	ENSMAUP00000013280	Interleukin-18 receptor 1.	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	0.985
Il18r1	Il1a	ENSMAUP00000020245	ENSMAUP00000020526	Interleukin-18 receptor 1.	Interleukin-1; Belongs to the IL-1 family.	0.800
Il18r1	Il1b	ENSMAUP00000020245	ENSMAUP00000019099	Interleukin-18 receptor 1.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.807
Il18r1	Il1f10	ENSMAUP00000020245	ENSMAUP00000023502	Interleukin-18 receptor 1.	Interleukin-1.	0.704
Il18r1	Il1f8	ENSMAUP00000020245	ENSMAUP00000001323	Interleukin-18 receptor 1.	Interleukin-1.	0.622
Il18r1	Il1r1	ENSMAUP00000020245	ENSMAUP00000000598	Interleukin-18 receptor 1.	Interleukin-1 receptor type 1.	0.732
Il18r1	Il1rap	ENSMAUP00000020245	ENSMAUP00000024453	Interleukin-18 receptor 1.	Interleukin-1 receptor accessory protein.	0.731
Il18r1	Il1rl1	ENSMAUP00000020245	ENSMAUP00000013887	Interleukin-18 receptor 1.	Interleukin-1 receptor-like 1.	0.601
Il18r1	Il1rl2	ENSMAUP00000020245	ENSMAUP00000015737	Interleukin-18 receptor 1.	Interleukin-1 receptor-like 2.	0.687
Il18r1	Il36rn	ENSMAUP00000020245	ENSMAUP00000023686	Interleukin-18 receptor 1.	Interleukin-1.	0.682
Il1a	Il18	ENSMAUP00000020526	ENSMAUP00000013280	Interleukin-1; Belongs to the IL-1 family.	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	0.691

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