Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Hoxa13Homeobox protein Hox-A13. (215 aa)    
Predicted Functional Partners:
Meis1
Homeobox protein Meis1 isoform X1.
    
 
 0.845
Meis2
Homeobox protein Meis2 isoform X3.
    
 
 0.684
Dot1l
Histone-lysine N-methyltransferase, H3 lysine-79 specific.
    
 
 0.517
Hoxa10
Homeobox protein Hox-A10 isoform X1.
   
  
 0.507
Six2
Homeobox protein SIX2.
     
 0.501
Hand2
Heart- and neural crest derivatives-expressed protein 2.
    
 
 0.499
Lim2
Lens fiber membrane intrinsic protein; Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis; Belongs to the PMP-22/EMP/MP20 family.
   
  
 0.484
Glcci1
Glucocorticoid-induced transcript 1 protein isoform X1.
      
 0.483
Poc5
Centrosomal protein POC5.
      
 0.480
Emx2
Homeobox protein EMX2.
    
 
 0.470
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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