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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Igsf10Immunoglobulin superfamily member 10. (2585 aa)    
Predicted Functional Partners:
Ptk7
Inactive tyrosine-protein kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
0.697
Cd47
Leukocyte surface antigen CD47 isoform X2.
    
  0.634
ENSMAUP00000013047
annotation not available
    
  0.565
Ptpn11
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
    
  0.565
Ap2s1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
  0.560
Ap2m1
AP-2 complex subunit mu; Belongs to the adaptor complexes medium subunit family.
    
  0.560
Il1b
Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.
   
  0.551
Il1a
Interleukin-1; Belongs to the IL-1 family.
   
  0.551
Egflam
Pikachurin.
    
 0.549
Fcgr4
Low affinity immunoglobulin gamma Fc region receptor III-like precursor.
    
  0.541
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.