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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E2f4Transcription factor E2F4. (81 aa)    
Predicted Functional Partners:
Tfdp2
Transcription factor.
   
 0.998
Tfdp1
Transcription factor.
  
 0.997
Rbl2
Retinoblastoma-like protein 2 isoform X2.
   
 0.992
Rbl1
Retinoblastoma-like protein 1 isoform X1.
   
 0.988
Rb1
Retinoblastoma-associated protein.
   
 0.988
Lin9
Protein lin-9 homolog.
    
 0.955
Smad3
Mothers against decapentaplegic homolog.
    
 0.946
E2f5
Transcription factor E2F5 isoform X1.
  
 
0.945
E2f3
Transcription factor E2F3 isoform X1.
  
 
0.942
Smad4
Mothers against decapentaplegic homolog.
    
 0.938
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.