close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (461 aa)    
Predicted Functional Partners:
Pole3
DNA polymerase epsilon subunit 3.
    
 0.999
Pole4
DNA polymerase epsilon subunit 4.
    
 0.999
Mcm2
DNA helicase; Belongs to the MCM family.
   
 0.999
Mcm3
DNA helicase; Belongs to the MCM family.
   
 0.999
Cdc45
Cell division control protein 45 homolog.
   
 0.999
Mcm4
DNA helicase; Belongs to the MCM family.
   
 0.999
Mcm5
DNA helicase; Belongs to the MCM family.
   
 0.999
Mcm6
DNA helicase; Belongs to the MCM family.
   
 0.998
Pola1
DNA polymerase.
   
 0.997
Wdhd1
WD repeat and HMG-box DNA-binding protein 1.
   
 
 0.997
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
Server load: low (38%) [HD]