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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Per3LOW QUALITY PROTEIN: period circadian protein homolog 3. (515 aa)    
Predicted Functional Partners:
Cry2
Cryptochrome-2.
   
 0.999
Cry1
Cryptochrome circadian regulator 1.
   
 0.999
Per2
Period circadian protein homolog 2.
  
0.998
Per1
Period circadian protein homolog 1 isoform X1.
    
0.998
Arntl
Aryl hydrocarbon receptor nuclear translocator-like protein 1; Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressur [...]
    
0.996
Clock
Circadian locomoter output cycles protein kaput.
    
0.981
Csnk1e
Casein kinase I isoform X2; Belongs to the protein kinase superfamily.
    
 0.976
Csnk1d
Casein kinase I isoform X1; Belongs to the protein kinase superfamily.
    
 0.976
Timeless
Protein timeless homolog.
   
 0.970
Npas2
Neuronal PAS domain-containing protein 2.
    
 0.963
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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