Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TonslTonsoku-like protein. (1363 aa)    
Predicted Functional Partners:
Ssrp1
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
   
 
 0.992
Asf1a
Histone chaperone ASF1A.
   
 
 0.992
Mcm2
DNA helicase; Belongs to the MCM family.
   
 
 0.989
Mms22l
Protein MMS22-like.
    
 
 0.988
Asf1b
Histone chaperone ASF1B.
   
 
 0.981
Mcm6
DNA helicase; Belongs to the MCM family.
   
 
 0.930
Traf7
E3 ubiquitin-protein ligase TRAF7 isoform X2.
    
 0.904
ENSMAUP00000006643
annotation not available
    
 0.900
Wdr90
WD repeat-containing protein 90.
   
 0.884
Nme8
Thioredoxin domain-containing protein 3 isoform X1.
    
 0.883
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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