node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Adk | Adsl | ENSMAUP00000001830 | ENSMAUP00000001467 | Adenosine kinase isoform X1. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.951 |
Adk | Adss | ENSMAUP00000001830 | ENSMAUP00000018706 | Adenosine kinase isoform X1. | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.812 |
Adk | Adss1 | ENSMAUP00000001830 | ENSMAUP00000020522 | Adenosine kinase isoform X1. | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.812 |
Adk | Ampd1 | ENSMAUP00000001830 | ENSMAUP00000001524 | Adenosine kinase isoform X1. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.905 |
Adk | Aprt | ENSMAUP00000001830 | ENSMAUP00000024444 | Adenosine kinase isoform X1. | Adenine phosphoribosyltransferase. | 0.935 |
Adk | Atic | ENSMAUP00000001830 | ENSMAUP00000013055 | Adenosine kinase isoform X1. | Bifunctional purine biosynthesis protein PURH. | 0.833 |
Adk | ENSMAUP00000012673 | ENSMAUP00000001830 | ENSMAUP00000012673 | Adenosine kinase isoform X1. | annotation not available | 0.935 |
Adk | Gmpr | ENSMAUP00000001830 | ENSMAUP00000013283 | Adenosine kinase isoform X1. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.439 |
Adk | Gmpr2 | ENSMAUP00000001830 | ENSMAUP00000015908 | Adenosine kinase isoform X1. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.439 |
Adk | Nt5c1b | ENSMAUP00000001830 | ENSMAUP00000020365 | Adenosine kinase isoform X1. | Cytosolic 5'-nucleotidase 1B isoform X5. | 0.851 |
Adsl | Adk | ENSMAUP00000001467 | ENSMAUP00000001830 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenosine kinase isoform X1. | 0.951 |
Adsl | Adss | ENSMAUP00000001467 | ENSMAUP00000018706 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.994 |
Adsl | Adss1 | ENSMAUP00000001467 | ENSMAUP00000020522 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.994 |
Adsl | Ampd1 | ENSMAUP00000001467 | ENSMAUP00000001524 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.928 |
Adsl | Aprt | ENSMAUP00000001467 | ENSMAUP00000024444 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenine phosphoribosyltransferase. | 0.957 |
Adsl | Atic | ENSMAUP00000001467 | ENSMAUP00000013055 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Bifunctional purine biosynthesis protein PURH. | 0.998 |
Adsl | ENSMAUP00000012673 | ENSMAUP00000001467 | ENSMAUP00000012673 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | annotation not available | 0.957 |
Adsl | Gmpr | ENSMAUP00000001467 | ENSMAUP00000013283 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.792 |
Adsl | Gmpr2 | ENSMAUP00000001467 | ENSMAUP00000015908 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.792 |
Adsl | Nt5c1b | ENSMAUP00000001467 | ENSMAUP00000020365 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Cytosolic 5'-nucleotidase 1B isoform X5. | 0.887 |