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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ssbp3Single-stranded DNA-binding protein 3 isoform X2. (388 aa)    
Predicted Functional Partners:
Ldb1
LIM domain-binding protein 1 isoform X1.
    
 
 0.837
Ldb2
LIM domain-binding protein 2 isoform X1.
    
 
 0.794
Ssbp2
Single-stranded DNA-binding protein 2 isoform X2.
  
 
 
0.629
Lhx9
LIM/homeobox protein Lhx9.
    
 
 0.622
Isl1
Insulin gene enhancer protein ISL-1; DNA-binding transcriptional activator. Recognizes and binds to the consensus octamer binding site 5'-ATAATTAA-3' in promoter of target genes. Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. Cooperates with the transcription factor POU4F2 to achieve maximal levels of expression of RGC target genes and RGC fate specification in the developing retina. Involved in the specification of motor neurons in cooperation with LHX3 and LDB1. Binds to insulin gene enhancer sequences. Essential for [...]
    
 
 0.619
Isl2
Insulin gene enhancer protein ISL-2.
    
 
 0.614
Lhx3
LIM/homeobox protein Lhx3 isoform X1.
    
 
 0.606
Lmo4
LIM domain transcription factor LMO4.
    
 
 0.604
Rnf11
RING finger protein 11.
   
    0.596
Lmx1b
LIM homeobox transcription factor 1-beta; Essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels. Mediates physical interaction and transcriptional synergy with E47/PAN-1.
    
   0.590
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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