Mkrn1 protein (Mesocricetus auratus) - STRING interaction network

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Mkrn1

E3 ubiquitin-protein ligase makorin-1. (271 aa)

Predicted Functional Partners:

LOC101838958

0.733

ENSMAUP00000004375

0.733

Fech

0.702

Cpsf2

0.668

Sri

0.647

Rps27a

0.641

ENSMAUP00000019431

0.641

Tpte

0.589

Pten

0.589

Atg7

0.542

Your Current Organism:

Mesocricetus auratus

NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atg7	ENSMAUP00000004375	ENSMAUP00000003166	ENSMAUP00000004375	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	annotation not available	0.982
Atg7	ENSMAUP00000019431	ENSMAUP00000003166	ENSMAUP00000019431	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	annotation not available	0.783
Atg7	LOC101838958	ENSMAUP00000003166	ENSMAUP00000000233	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	E3 ubiquitin-protein ligase TRIP12.	0.982
Atg7	Mkrn1	ENSMAUP00000003166	ENSMAUP00000001609	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	E3 ubiquitin-protein ligase makorin-1.	0.542
Atg7	Rps27a	ENSMAUP00000003166	ENSMAUP00000005833	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	ubiquitin-40S ribosomal protein S27a.	0.783
Cpsf2	Mkrn1	ENSMAUP00000015799	ENSMAUP00000001609	Cleavage and polyadenylation specificity factor subunit 2.	E3 ubiquitin-protein ligase makorin-1.	0.668
ENSMAUP00000004375	Atg7	ENSMAUP00000004375	ENSMAUP00000003166	annotation not available	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.982
ENSMAUP00000004375	ENSMAUP00000019431	ENSMAUP00000004375	ENSMAUP00000019431	annotation not available	annotation not available	0.848
ENSMAUP00000004375	LOC101838958	ENSMAUP00000004375	ENSMAUP00000000233	annotation not available	E3 ubiquitin-protein ligase TRIP12.	0.874
ENSMAUP00000004375	Mkrn1	ENSMAUP00000004375	ENSMAUP00000001609	annotation not available	E3 ubiquitin-protein ligase makorin-1.	0.733
ENSMAUP00000004375	Rps27a	ENSMAUP00000004375	ENSMAUP00000005833	annotation not available	ubiquitin-40S ribosomal protein S27a.	0.848
ENSMAUP00000019431	Atg7	ENSMAUP00000019431	ENSMAUP00000003166	annotation not available	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.783
ENSMAUP00000019431	ENSMAUP00000004375	ENSMAUP00000019431	ENSMAUP00000004375	annotation not available	annotation not available	0.848
ENSMAUP00000019431	LOC101838958	ENSMAUP00000019431	ENSMAUP00000000233	annotation not available	E3 ubiquitin-protein ligase TRIP12.	0.848
ENSMAUP00000019431	Mkrn1	ENSMAUP00000019431	ENSMAUP00000001609	annotation not available	E3 ubiquitin-protein ligase makorin-1.	0.641
ENSMAUP00000019431	Pten	ENSMAUP00000019431	ENSMAUP00000004646	annotation not available	Phosphatase and tensin homolog.	0.703
ENSMAUP00000019431	Tpte	ENSMAUP00000019431	ENSMAUP00000000347	annotation not available	LOW QUALITY PROTEIN: phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2-like.	0.686
Fech	Mkrn1	ENSMAUP00000002318	ENSMAUP00000001609	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	E3 ubiquitin-protein ligase makorin-1.	0.702
Fech	Sri	ENSMAUP00000002318	ENSMAUP00000008389	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	Sorcin isoform X2.	0.761
LOC101838958	Atg7	ENSMAUP00000000233	ENSMAUP00000003166	E3 ubiquitin-protein ligase TRIP12.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.982

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