Hbegf protein (Mesocricetus auratus) - STRING interaction network

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Score

Hbegf

Proheparin-binding EGF-like growth factor. (202 aa)

Predicted Functional Partners:

Erbb4

0.956

Egfr

0.951

Ereg

0.921

Mmp9

0.867

Gpc1

0.857

Erbb2

0.854

Mmp14

0.850

Mmp16

0.843

Mmp15

0.843

Btc

0.839

Your Current Organism:

Mesocricetus auratus

NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Btc	Egfr	ENSMAUP00000000250	ENSMAUP00000000794	Probetacellulin.	Receptor protein-tyrosine kinase.	0.983
Btc	Erbb2	ENSMAUP00000000250	ENSMAUP00000024426	Probetacellulin.	Receptor tyrosine-protein kinase erbB-2; Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and [...]	0.867
Btc	Erbb4	ENSMAUP00000000250	ENSMAUP00000024513	Probetacellulin.	Receptor protein-tyrosine kinase.	0.958
Btc	Ereg	ENSMAUP00000000250	ENSMAUP00000014069	Probetacellulin.	Proepiregulin.	0.846
Btc	Hbegf	ENSMAUP00000000250	ENSMAUP00000001635	Probetacellulin.	Proheparin-binding EGF-like growth factor.	0.839
Egfr	Btc	ENSMAUP00000000794	ENSMAUP00000000250	Receptor protein-tyrosine kinase.	Probetacellulin.	0.983
Egfr	Erbb2	ENSMAUP00000000794	ENSMAUP00000024426	Receptor protein-tyrosine kinase.	Receptor tyrosine-protein kinase erbB-2; Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and [...]	0.999
Egfr	Erbb4	ENSMAUP00000000794	ENSMAUP00000024513	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.995
Egfr	Ereg	ENSMAUP00000000794	ENSMAUP00000014069	Receptor protein-tyrosine kinase.	Proepiregulin.	0.998
Egfr	Gpc1	ENSMAUP00000000794	ENSMAUP00000017119	Receptor protein-tyrosine kinase.	Glypican-1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.452
Egfr	Hbegf	ENSMAUP00000000794	ENSMAUP00000001635	Receptor protein-tyrosine kinase.	Proheparin-binding EGF-like growth factor.	0.951
Egfr	Mmp14	ENSMAUP00000000794	ENSMAUP00000020585	Receptor protein-tyrosine kinase.	Matrix metalloproteinase-14.	0.408
Egfr	Mmp9	ENSMAUP00000000794	ENSMAUP00000004494	Receptor protein-tyrosine kinase.	Matrix metalloproteinase-9.	0.568
Erbb2	Btc	ENSMAUP00000024426	ENSMAUP00000000250	Receptor tyrosine-protein kinase erbB-2; Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and [...]	Probetacellulin.	0.867
Erbb2	Egfr	ENSMAUP00000024426	ENSMAUP00000000794	Receptor tyrosine-protein kinase erbB-2; Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and [...]	Receptor protein-tyrosine kinase.	0.999
Erbb2	Erbb4	ENSMAUP00000024426	ENSMAUP00000024513	Receptor tyrosine-protein kinase erbB-2; Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and [...]	Receptor protein-tyrosine kinase.	0.995
Erbb2	Ereg	ENSMAUP00000024426	ENSMAUP00000014069	Receptor tyrosine-protein kinase erbB-2; Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and [...]	Proepiregulin.	0.949
Erbb2	Hbegf	ENSMAUP00000024426	ENSMAUP00000001635	Receptor tyrosine-protein kinase erbB-2; Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and [...]	Proheparin-binding EGF-like growth factor.	0.854
Erbb4	Btc	ENSMAUP00000024513	ENSMAUP00000000250	Receptor protein-tyrosine kinase.	Probetacellulin.	0.958
Erbb4	Egfr	ENSMAUP00000024513	ENSMAUP00000000794	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.995

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