| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bmt2 | CUNH12orf66 | ENSMAUP00000022440 | ENSMAUP00000001636 | S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] | UPF0536 protein C12orf66 homolog. | 0.936 |
| Bmt2 | Depdc5 | ENSMAUP00000022440 | ENSMAUP00000003554 | S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] | DEP domain-containing protein 5. | 0.903 |
| Bmt2 | Itfg2 | ENSMAUP00000022440 | ENSMAUP00000007967 | S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] | Integrin-alpha FG-GAP repeat-containing protein 2. | 0.919 |
| Bmt2 | Kptn | ENSMAUP00000022440 | ENSMAUP00000001170 | S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] | Kaptin isoform X2. | 0.836 |
| Bmt2 | Nprl2 | ENSMAUP00000022440 | ENSMAUP00000019058 | S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] | Nitrogen permease regulator 2-like protein. | 0.864 |
| Bmt2 | Nprl3 | ENSMAUP00000022440 | ENSMAUP00000001014 | S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] | Nitrogen permease regulator 3-like protein. | 0.838 |
| CUNH12orf66 | Bmt2 | ENSMAUP00000001636 | ENSMAUP00000022440 | UPF0536 protein C12orf66 homolog. | S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] | 0.936 |
| CUNH12orf66 | Depdc5 | ENSMAUP00000001636 | ENSMAUP00000003554 | UPF0536 protein C12orf66 homolog. | DEP domain-containing protein 5. | 0.997 |
| CUNH12orf66 | Itfg2 | ENSMAUP00000001636 | ENSMAUP00000007967 | UPF0536 protein C12orf66 homolog. | Integrin-alpha FG-GAP repeat-containing protein 2. | 0.999 |
| CUNH12orf66 | Kptn | ENSMAUP00000001636 | ENSMAUP00000001170 | UPF0536 protein C12orf66 homolog. | Kaptin isoform X2. | 0.998 |
| CUNH12orf66 | Mios | ENSMAUP00000001636 | ENSMAUP00000008555 | UPF0536 protein C12orf66 homolog. | WD repeat-containing protein mio. | 0.762 |
| CUNH12orf66 | Nprl2 | ENSMAUP00000001636 | ENSMAUP00000019058 | UPF0536 protein C12orf66 homolog. | Nitrogen permease regulator 2-like protein. | 0.996 |
| CUNH12orf66 | Nprl3 | ENSMAUP00000001636 | ENSMAUP00000001014 | UPF0536 protein C12orf66 homolog. | Nitrogen permease regulator 3-like protein. | 0.834 |
| CUNH12orf66 | Ppp1r3a | ENSMAUP00000001636 | ENSMAUP00000020402 | UPF0536 protein C12orf66 homolog. | Protein phosphatase 1 regulatory subunit 3A. | 0.858 |
| CUNH12orf66 | Wdr24 | ENSMAUP00000001636 | ENSMAUP00000024835 | UPF0536 protein C12orf66 homolog. | WD repeat-containing protein 24. | 0.996 |
| CUNH12orf66 | Wdr59 | ENSMAUP00000001636 | ENSMAUP00000012990 | UPF0536 protein C12orf66 homolog. | WD repeat-containing protein 59. | 0.996 |
| Depdc5 | Bmt2 | ENSMAUP00000003554 | ENSMAUP00000022440 | DEP domain-containing protein 5. | S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] | 0.903 |
| Depdc5 | CUNH12orf66 | ENSMAUP00000003554 | ENSMAUP00000001636 | DEP domain-containing protein 5. | UPF0536 protein C12orf66 homolog. | 0.997 |
| Depdc5 | Itfg2 | ENSMAUP00000003554 | ENSMAUP00000007967 | DEP domain-containing protein 5. | Integrin-alpha FG-GAP repeat-containing protein 2. | 0.997 |
| Depdc5 | Kptn | ENSMAUP00000003554 | ENSMAUP00000001170 | DEP domain-containing protein 5. | Kaptin isoform X2. | 0.996 |
STRING v12.5 is now available!
