close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Adh5S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (343 aa)    
Predicted Functional Partners:
Esd
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
 0.991
Adhfe1
Hydroxyacid-oxoacid transhydrogenase, mitochondrial isoform X2.
  
 0.958
Aldh3a1
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.919
Aldh2
Aldehyde dehydrogenase, mitochondrial; Belongs to the aldehyde dehydrogenase family.
  
 0.905
Aldh1a1
Retinal dehydrogenase 1; Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo (By similarity).
  
 0.899
Aldh3b1
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.898
Aldh3a2
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.892
Aldh7a1
Alpha-aminoadipic semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.891
Aldh9a1
4-trimethylaminobutyraldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.889
Aldh1b1
Aldehyde dehydrogenase X, mitochondrial; Belongs to the aldehyde dehydrogenase family.
  
 0.888
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.