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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Fxr1Fragile X mental retardation syndrome-related protein 1 isoform X1. (677 aa)    
Predicted Functional Partners:
Fxr2
Fragile X mental retardation syndrome-related protein 2.
  
 
0.991
Cyfip2
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
    
 0.967
Cyfip1
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
    
 0.964
Fmr1
Synaptic functional regulator FMR1.
    
0.951
LOC101824858
Synaptic functional regulator FMR1.
  
 
0.948
Ago2
Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]
    
 
 0.768
Ago1
Protein argonaute-1 isoform X1; Belongs to the argonaute family.
    
 
 0.767
Tdrd3
Tudor domain-containing protein 3 isoform X1.
    
 
 0.762
G3bp1
Ras GTPase-activating protein-binding protein 1.
    
 
 0.729
Serbp1
Plasminogen activator inhibitor 1 RNA-binding protein.
    
 
 0.679
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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