| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Il4 | Lamtor1 | ENSMAUP00000007897 | ENSMAUP00000005575 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] | Ragulator complex protein LAMTOR1. | 0.972 |
| Il4 | Lamtor2 | ENSMAUP00000007897 | ENSMAUP00000000695 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] | Ragulator complex protein LAMTOR2 isoform X1. | 0.981 |
| Il4 | Lamtor4 | ENSMAUP00000007897 | ENSMAUP00000025178 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] | Ragulator complex protein LAMTOR4 isoform X1. | 0.970 |
| Il4 | Rragc | ENSMAUP00000007897 | ENSMAUP00000012310 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] | Ras-related GTP-binding protein C. | 0.965 |
| Il4 | Rragd | ENSMAUP00000007897 | ENSMAUP00000025087 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] | Ras-related GTP-binding protein D isoform X1. | 0.965 |
| Il4 | Slc36a1 | ENSMAUP00000007897 | ENSMAUP00000006028 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] | Proton-coupled amino acid transporter 1 isoform X1. | 0.664 |
| Il4 | Slc36a2 | ENSMAUP00000007897 | ENSMAUP00000011496 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] | Proton-coupled amino acid transporter 2. | 0.664 |
| Il4 | Slc36a3 | ENSMAUP00000007897 | ENSMAUP00000009112 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] | Proton-coupled amino acid transporter 3. | 0.664 |
| Il4 | Slc36a4 | ENSMAUP00000007897 | ENSMAUP00000001728 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] | Proton-coupled amino acid transporter 4 isoform X1. | 0.664 |
| Lamtor1 | Il4 | ENSMAUP00000005575 | ENSMAUP00000007897 | Ragulator complex protein LAMTOR1. | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] | 0.972 |
| Lamtor1 | Lamtor2 | ENSMAUP00000005575 | ENSMAUP00000000695 | Ragulator complex protein LAMTOR1. | Ragulator complex protein LAMTOR2 isoform X1. | 0.999 |
| Lamtor1 | Lamtor4 | ENSMAUP00000005575 | ENSMAUP00000025178 | Ragulator complex protein LAMTOR1. | Ragulator complex protein LAMTOR4 isoform X1. | 0.999 |
| Lamtor1 | Rraga | ENSMAUP00000005575 | ENSMAUP00000003399 | Ragulator complex protein LAMTOR1. | Ras-related GTP-binding protein A. | 0.993 |
| Lamtor1 | Rragc | ENSMAUP00000005575 | ENSMAUP00000012310 | Ragulator complex protein LAMTOR1. | Ras-related GTP-binding protein C. | 0.999 |
| Lamtor1 | Rragd | ENSMAUP00000005575 | ENSMAUP00000025087 | Ragulator complex protein LAMTOR1. | Ras-related GTP-binding protein D isoform X1. | 0.998 |
| Lamtor1 | Slc36a1 | ENSMAUP00000005575 | ENSMAUP00000006028 | Ragulator complex protein LAMTOR1. | Proton-coupled amino acid transporter 1 isoform X1. | 0.656 |
| Lamtor1 | Slc36a2 | ENSMAUP00000005575 | ENSMAUP00000011496 | Ragulator complex protein LAMTOR1. | Proton-coupled amino acid transporter 2. | 0.651 |
| Lamtor1 | Slc36a3 | ENSMAUP00000005575 | ENSMAUP00000009112 | Ragulator complex protein LAMTOR1. | Proton-coupled amino acid transporter 3. | 0.644 |
| Lamtor1 | Slc36a4 | ENSMAUP00000005575 | ENSMAUP00000001728 | Ragulator complex protein LAMTOR1. | Proton-coupled amino acid transporter 4 isoform X1. | 0.659 |
| Lamtor2 | Il4 | ENSMAUP00000000695 | ENSMAUP00000007897 | Ragulator complex protein LAMTOR2 isoform X1. | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] | 0.981 |