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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101831088Cytochrome P450 2C26; Catalyzes the hydroxylation of tolbutamide and the N- demethylation of aminopyrine and benzphetamine. (490 aa)    
Predicted Functional Partners:
Suox
Sulfite oxidase, mitochondrial.
     
 0.857
Aasdh
acyl-CoA synthetase family member 4 isoform X1.
  
 0.798
Ephx2
Bifunctional epoxide hydrolase 2.
   
 0.752
Cyp17a1
Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...]
  
 
0.730
LOC101836914
Cytochrome P450 3A31; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
  
0.728
Cyb5r4
Cytochrome b5 reductase 4 isoform X1.
   
 0.724
Cyp26b1
Cytochrome P450 26B1; Belongs to the cytochrome P450 family.
  
0.718
Lss
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
   
 0.717
ENSMAUP00000000801
annotation not available
  
 0.715
LOC110340045
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 0.715
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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