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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ppip5k1Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1469 aa)    
Predicted Functional Partners:
Ip6k1
Kinase; Belongs to the inositol phosphokinase (IPK) family.
    
 0.945
Ip6k3
Kinase; Belongs to the inositol phosphokinase (IPK) family.
    
 0.944
Ip6k2
Kinase; Belongs to the inositol phosphokinase (IPK) family.
    
 0.942
Ippk
Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
     
 0.900
LOC101834878
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2.
  
  
 
0.846
Ipmk
Kinase; Belongs to the inositol phosphokinase (IPK) family.
    
 0.704
Tasor
Protein TASOR-like.
    
 0.690
Bckdk
Protein-serine/threonine kinase.
     
 0.599
Pdk4
Protein-serine/threonine kinase.
     
 0.599
Pdk1
Protein-serine/threonine kinase.
     
 0.599
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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