STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TollipToll-interacting protein. (274 aa)    
Predicted Functional Partners:
Irak1
Interleukin-1 receptor-associated kinase 1 isoform X2.
   
 0.983
Irak4
Interleukin-1 receptor-associated kinase 4.
   
 0.961
Tom1
Target of Myb protein 1 isoform X2; Belongs to the TOM1 family.
    
 
 0.956
Myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.942
Tlr2
Toll-like receptor.
    
 0.941
Tirap
Toll/interleukin-1 receptor domain-containing adapter protein isoform X2.
     
 0.893
Traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.890
Il1r1
Interleukin-1 receptor type 1.
    
 0.886
Tom1l2
TOM1-like protein 2 isoform X3; Belongs to the TOM1 family.
    
 
 0.875
Met
Hepatocyte growth factor receptor.
    
  0.821
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.