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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Traf5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (550 aa)    
Predicted Functional Partners:
Traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
0.997
Tbk1
Serine/threonine-protein kinase TBK1.
   
 0.996
Mavs
Mitochondrial antiviral-signaling protein isoform X1.
    
 0.987
Ripk1
Receptor-interacting serine/threonine-protein kinase 1.
   
 0.975
Traf3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
  
0.973
Tradd
Tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X2.
    
 0.972
Tank
TRAF family member-associated NF-kappa-B activator isoform X2.
    
 0.967
Ltbr
Tumor necrosis factor receptor superfamily member 3.
    
 0.965
Tnfrsf13c
TNF receptor superfamily member 13C.
   
 0.964
Ikbke
Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1.
   
 0.961
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.