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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MndaMyeloid cell nuclear differentiation antigen. (480 aa)    
Predicted Functional Partners:
Tmem173
Stimulator of interferon genes protein.
   
 0.904
Pycard
Apoptosis-associated speck-like protein containing a CARD.
   
 0.880
Aim2
Interferon-inducible protein AIM2.
  
 
0.821
Ifi209
Pyrin and HIN domain-containing protein 1-like.
  
  
 
0.700
Tp53bp1
TP53-binding protein 1 isoform X2.
    
 0.669
Tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]
    
 
 0.535
Itsn1
Intersectin-1.
    
  0.512
Itsn2
Intersectin-2.
    
  0.512
ENSMAUP00000006643
annotation not available
    
 
 0.511
Arhgef1
Rho guanine nucleotide exchange factor 1.
  
 
 0.482
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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