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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSMAUP00000001893annotation not available (410 aa)    
Predicted Functional Partners:
OAZ1
Ornithine decarboxylase antizyme 1; Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin- independent proteolytic destruction by the 26S proteasome. Triggers ODC degradation by inducing the exposure of a cryptic proteasome- interacting surface of ODC. Stabilizes AZIN2 by interfering with its ubiquitination. Also inhibits cellular [...]
    
 0.937
Aass
Alpha-aminoadipic semialdehyde synthase, mitochondrial isoform X1.
  
 
 0.850
Oaz2
Ornithine decarboxylase antizyme 2.
    
 0.839
Oaz3
Ornithine decarboxylase antizyme 3 isoform 1.
    
 0.837
Srm
Spermidine synthase; Belongs to the spermidine/spermine synthase family.
  
 0.828
Sms
LOW QUALITY PROTEIN: spermine synthase.
  
 0.811
Ass1
Argininosuccinate synthase.
  
 
 0.798
Agmat
Agmatinase, mitochondrial; Belongs to the arginase family.
  
 
 0.794
Oat
Ornithine aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
    
 0.792
Crym
Ketimine reductase mu-crystallin.
  
 
 0.784
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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