Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Csf3rGranulocyte colony-stimulating factor receptor. (624 aa)    
Predicted Functional Partners:
Csf3
Granulocyte colony-stimulating factor.
    
 0.999
Jak1
Tyrosine-protein kinase.
   
 0.987
Jak2
Tyrosine-protein kinase.
   
 0.964
Jak3
Tyrosine-protein kinase.
   
 0.951
Grb2
Growth factor receptor-bound protein 2.
    
  0.949
Epor
Erythropoietin receptor; Receptor for erythropoietin.
     
 0.935
Shc1
SHC-transforming protein 1 isoform X1.
    
 0.935
Mpl
Thrombopoietin receptor isoform X1.
     
 0.932
Lyn
Tyrosine-protein kinase.
   
 0.915
Osm
oncostatin-M isoform X2.
   
 0.913
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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