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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Kpna4Importin subunit alpha; Functions in nuclear protein import. (502 aa)    
Predicted Functional Partners:
Rela
Transcription factor p65 isoform X1.
    
 0.991
Nfkb1
Nuclear factor NF-kappa-B p105 subunit isoform X1.
    
 0.983
Rcc1
Regulator of chromosome condensation; Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis. Contributes to the generation of high levels of chromosome-associated, GTP-bound RAN, which is important for mitotic spindle assembly and normal progress through mitosis. Via its role in maintaining high levels of GTP-bound RAN in the nucleus, contributes to the release of cargo proteins from importins after nuclear import (By similarity). Involved in the regulation of o [...]
   
 
 0.974
Cse1l
Exportin-2 isoform X1.
   
 0.973
Kpna3
Importin subunit alpha; Functions in nuclear protein import.
  
0.964
Kpnb1
Importin subunit beta-1.
   
 0.958
ENSMAUP00000023860
annotation not available
  
0.930
Nfkb2
Nuclear factor NF-kappa-B p100 subunit isoform X2.
    
  0.918
Ranbp3
Ran-binding protein 3 isoform X2.
    
 
 0.907
Tp53bp1
TP53-binding protein 1 isoform X2.
    
   0.900
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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