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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ch25hCholesterol 25-hydroxylase; Belongs to the sterol desaturase family. (284 aa)    
Predicted Functional Partners:
Sc5d
Lathosterol oxidase; Belongs to the sterol desaturase family.
   
 0.995
LOC101826047
Lanosterol 14-alpha demethylase; Belongs to the cytochrome P450 family.
  
 0.992
Sqle
Squalene monooxygenase.
   
 0.989
Hsd17b7
3-keto-steroid reductase.
   
 0.985
Sigmar1
Sigma non-opioid intracellular receptor 1 isoform X1.
   
 0.981
Cyp7a1
Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.
  
 0.979
Cyp7b1
25-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family.
  
 0.979
Nsdhl
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; Belongs to the 3-beta-HSD family.
  
 0.978
Fdft1
Squalene synthase.
  
 0.978
Dhcr7
7-dehydrocholesterol reductase.
   
 0.960
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.