STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Abcc8ATP-binding cassette sub-family C member 8 isoform X2. (1582 aa)    
Predicted Functional Partners:
Kcnj11
ATP-sensitive inward rectifier potassium channel 11 isoform X1.
 
 
 0.999
Kcnj8
ATP-sensitive inward rectifier potassium channel 8.
   
 0.990
Rapgef4
Rap guanine nucleotide exchange factor 4 isoform X1.
    
 0.943
Prkacb
cAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily.
 
 
 0.866
Prkaca
cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily.
 
 
 0.866
Rapgef3
Rap guanine nucleotide exchange factor 3 isoform X4.
    
 0.805
Kcnj6
G protein-activated inward rectifier potassium channel 2; This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G- protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due t [...]
 
 
 0.793
Stx1a
syntaxin-1A isoform X1; Belongs to the syntaxin family.
    
 0.743
Kcnj1
ATP-sensitive inward rectifier potassium channel 1 isoform X1.
    
 0.739
Kcnj12
ATP-sensitive inward rectifier potassium channel 12 isoform X2.
    
 0.724
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.