STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pla2g2ePhospholipase A(2). (147 aa)    
Predicted Functional Partners:
Pla2g12a
Group XIIA secretory phospholipase A2.
     
 0.901
Pla2g12b
Group XIIB secretory phospholipase A2-like protein isoform X1.
     
 0.892
Pla2g4a
Phospholipase A2.
     
 0.891
Pla2g3
Group 3 secretory phospholipase A2.
     
 0.884
Plaat3
HRAS-like suppressor 3.
     
 0.869
Pla2g6
85/88 kDa calcium-independent phospholipase A2.
   
 
 0.863
Ptgs1
Prostaglandin G/H synthase 1.
     
 0.858
Ptgs2
Prostaglandin G/H synthase 2.
     
 0.858
Pafah1b2
Platelet-activating factor acetylhydrolase IB subunit beta.
     
 0.858
LOC101843716
Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.
     
 0.857
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.