STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101830103Cytochrome P450 4F5 isoform X1; Belongs to the cytochrome P450 family. (524 aa)    
Predicted Functional Partners:
Aasdh
acyl-CoA synthetase family member 4 isoform X1.
  
 0.823
Pla2g4a
Phospholipase A2.
    
 0.818
Suox
Sulfite oxidase, mitochondrial.
     
 0.817
Lss
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
   
 0.803
Cyp2u1
Cytochrome P450 2U1; Belongs to the cytochrome P450 family.
  
0.780
Cyp2c70
Cytochrome P450 2C70-like; Belongs to the cytochrome P450 family.
  
0.776
LOC101843716
Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.
  
0.770
Cyb5r4
Cytochrome b5 reductase 4 isoform X1.
   
 0.760
Pla2g3
Group 3 secretory phospholipase A2.
    
 0.757
Hsd17b7
3-keto-steroid reductase.
    
 0.739
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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