STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cryba1Beta-crystallin A3; Belongs to the beta/gamma-crystallin family. (222 aa)    
Predicted Functional Partners:
Cryaa
Alpha-crystallin A chain; Contributes to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA; Belongs to the small heat shock protein (HSP20) family.
   
 
 0.932
Cryab
Alpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions; Belongs to the small heat shock protein (HSP20) family.
   
 
 0.754
Crybb1
Beta-crystallin B1; Belongs to the beta/gamma-crystallin family.
  
 
0.721
Crybb2
Beta-crystallin B2; Crystallins are the dominant structural components of the vertebrate eye lens.
  
  
0.681
Bfsp1
Filensin; Belongs to the intermediate filament family.
   
  
 0.656
Cryba2
Beta-crystallin A2; Belongs to the beta/gamma-crystallin family.
  
  
0.612
Best1
Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family.
   
  
 0.586
Gnat2
Guanine nucleotide-binding protein G(T) subunit alpha-2.
   
  
 0.584
Hspb7
Heat shock protein beta-7; Belongs to the small heat shock protein (HSP20) family.
   
 
 0.574
Hspb1
Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family.
   
 
 0.556
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.