STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Kctd6BTB/POZ domain-containing protein KCTD6 isoform X1. (237 aa)    
Predicted Functional Partners:
Cul3
Cullin-3; Belongs to the cullin family.
    
 0.957
Ube2m
NEDD8-conjugating enzyme Ubc12; Belongs to the ubiquitin-conjugating enzyme family.
    
  0.735
Btbd6
BTB/POZ domain-containing protein 6 isoform X1.
    
 0.705
Ube2f
NEDD8-conjugating enzyme UBE2F isoform X1; Belongs to the ubiquitin-conjugating enzyme family.
    
  0.699
Cul1
Cullin-1; Belongs to the cullin family.
    
 0.659
Kbtbd13
Kelch repeat and BTB domain-containing protein 13.
     
 0.657
Commd1
COMM domain-containing protein 1 isoform X2.
     
 0.646
Klhl25
Kelch-like protein 25.
    
 0.638
Nae1
NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
     
 0.632
Tfap2d
Transcription factor AP-2-delta isoform X2.
    
 0.622
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.