STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cacng3Voltage-dependent calcium channel gamma-3 subunit isoform X1. (315 aa)    
Predicted Functional Partners:
Gria2
Glutamate receptor 2 isoform X3.
    
 0.982
Ppp1cb
Protein phosphatase 1 catalytic subunit beta.
   
 0.922
Ppp1ca
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 0.920
Ppp1cc
Protein phosphatase 1 catalytic subunit gamma.
   
 0.916
Cacng2
Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
  
 
 
0.898
Ppp2ca
Serine/threonine-protein phosphatase.
    
 0.887
Ppp2r2d
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.
    
  0.876
Ppp2r2c
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.
    
  0.876
Camk2a
Calcium/calmodulin-dependent protein kinase type II subunit alpha; Belongs to the protein kinase superfamily.
    
  0.872
Ppp2r2b
Protein phosphatase 2, regulatory subunit B, beta.
    
 0.870
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.