STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arhgef12Rho guanine nucleotide exchange factor 12 isoform X1. (1544 aa)    
Predicted Functional Partners:
4930544G11Rik
Transforming protein RhoA-like isoform X1.
   
 0.979
Gna13
Guanine nucleotide-binding protein subunit alpha-13.
    
 0.972
Gna12
Guanine nucleotide-binding protein subunit alpha-12.
    
 0.971
Rhoa
Transforming protein RhoA-like isoform X2.
   
 0.963
Plxnb1
plexin-B1 isoform X2.
    
 0.961
Plxnb2
plexin-B2.
    
 0.959
Rhoc
Rho-related GTP-binding protein RhoC.
   
 0.943
Plxnb3
plexin-B3 isoform X2.
    
 0.941
Cd44
CD44 antigen; Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment. Participates thereby in a wide variety of cellular functions including the activation, recirculation and homing of T-lymphocytes, hematopoiesis, inflammation and response to bacterial infection. Engages, through its ectodomain, extracellular matrix components such as hyaluronan/HA, collagen, growth factors, cytokines or proteases and serves as a platform for signal transduction by assembling, via its c [...]
    
 0.918
Rras
Ras-related protein R-Ras.
    
 0.900
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.