node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F2 | F7 | ENSMAUP00000007879 | ENSMAUP00000009870 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Coagulation factor VII. | 0.921 |
F2 | Fgb | ENSMAUP00000007879 | ENSMAUP00000001266 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Fibrinogen beta chain. | 0.998 |
F2 | Fgg | ENSMAUP00000007879 | ENSMAUP00000002533 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Fibrinogen gamma chain isoform X1. | 0.998 |
F2 | Habp2 | ENSMAUP00000007879 | ENSMAUP00000010901 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Hyaluronan-binding protein 2 isoform X1; Belongs to the peptidase S1 family. | 0.538 |
F2 | LOC101835835-2 | ENSMAUP00000007879 | ENSMAUP00000016163 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Serine protease inhibitor A3N-like isoform X2; Belongs to the serpin family. | 0.871 |
F2 | Proc | ENSMAUP00000007879 | ENSMAUP00000002547 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Vitamin K-dependent protein C isoform X2. | 0.993 |
F2 | Proz | ENSMAUP00000007879 | ENSMAUP00000025865 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Vitamin K-dependent protein Z isoform X1; Belongs to the peptidase S1 family. | 0.897 |
F2 | Serpinc1 | ENSMAUP00000007879 | ENSMAUP00000021913 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Antithrombin-III; Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin (By similarity). | 0.999 |
F2 | Serpind1 | ENSMAUP00000007879 | ENSMAUP00000011361 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Heparin cofactor 2; Belongs to the serpin family. | 0.998 |
F2 | Vtn | ENSMAUP00000007879 | ENSMAUP00000001926 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Vitronectin. | 0.774 |
F7 | F2 | ENSMAUP00000009870 | ENSMAUP00000007879 | Coagulation factor VII. | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.921 |
F7 | Fgb | ENSMAUP00000009870 | ENSMAUP00000001266 | Coagulation factor VII. | Fibrinogen beta chain. | 0.668 |
F7 | Fgg | ENSMAUP00000009870 | ENSMAUP00000002533 | Coagulation factor VII. | Fibrinogen gamma chain isoform X1. | 0.720 |
F7 | Habp2 | ENSMAUP00000009870 | ENSMAUP00000010901 | Coagulation factor VII. | Hyaluronan-binding protein 2 isoform X1; Belongs to the peptidase S1 family. | 0.463 |
F7 | LOC101835835-2 | ENSMAUP00000009870 | ENSMAUP00000016163 | Coagulation factor VII. | Serine protease inhibitor A3N-like isoform X2; Belongs to the serpin family. | 0.685 |
F7 | Proc | ENSMAUP00000009870 | ENSMAUP00000002547 | Coagulation factor VII. | Vitamin K-dependent protein C isoform X2. | 0.766 |
F7 | Serpinc1 | ENSMAUP00000009870 | ENSMAUP00000021913 | Coagulation factor VII. | Antithrombin-III; Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin (By similarity). | 0.967 |
F7 | Serpind1 | ENSMAUP00000009870 | ENSMAUP00000011361 | Coagulation factor VII. | Heparin cofactor 2; Belongs to the serpin family. | 0.784 |
Fgb | F2 | ENSMAUP00000001266 | ENSMAUP00000007879 | Fibrinogen beta chain. | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.998 |
Fgb | F7 | ENSMAUP00000001266 | ENSMAUP00000009870 | Fibrinogen beta chain. | Coagulation factor VII. | 0.668 |