STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlx1T-cell leukemia homeobox protein 1 isoform X2. (333 aa)    
Predicted Functional Partners:
Eya1
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
    
 
 0.621
Arx
Homeobox protein ARX.
    
 
0.594
LOC101832402
Uncharacterized protein LOC101832402.
    
 
 0.594
Pax2
Paired box protein Pax-2 isoform X3.
      
 0.572
Fancm
Fanconi anemia group M protein.
     
 0.499
Lmo1
Rhombotin-1.
    
 
 0.484
Ercc4
DNA repair endonuclease XPF.
     
 0.463
Lmo2
Rhombotin-2 isoform X1.
    
 
 0.449
Lmx1a
LIM homeobox transcription factor 1-alpha; Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae (By similarity).
    
 
 0.449
Lmx1b
LIM homeobox transcription factor 1-beta; Essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels. Mediates physical interaction and transcriptional synergy with E47/PAN-1.
    
 
 0.449
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.