node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Coq2 | Fdft1 | ENSMAUP00000013272 | ENSMAUP00000022823 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Squalene synthase. | 0.776 |
Coq2 | Fdps | ENSMAUP00000013272 | ENSMAUP00000023841 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Farnesyl pyrophosphate synthase-like. | 0.797 |
Coq2 | Idi1 | ENSMAUP00000013272 | ENSMAUP00000018134 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Isopentenyl-diphosphate Delta-isomerase 1; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.881 |
Coq2 | Lss | ENSMAUP00000013272 | ENSMAUP00000004363 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. | 0.774 |
Coq2 | Mvd | ENSMAUP00000013272 | ENSMAUP00000022730 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. | 0.575 |
Coq2 | Rusc1 | ENSMAUP00000013272 | ENSMAUP00000018552 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | RUN and SH3 domain-containing protein 1 isoform X2. | 0.797 |
Coq2 | Sqle | ENSMAUP00000013272 | ENSMAUP00000003609 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Squalene monooxygenase. | 0.824 |
Coq2-2 | Fdft1 | ENSMAUP00000013903 | ENSMAUP00000022823 | Coenzyme Q2, polyprenyltransferase. | Squalene synthase. | 0.776 |
Coq2-2 | Fdps | ENSMAUP00000013903 | ENSMAUP00000023841 | Coenzyme Q2, polyprenyltransferase. | Farnesyl pyrophosphate synthase-like. | 0.797 |
Coq2-2 | Idi1 | ENSMAUP00000013903 | ENSMAUP00000018134 | Coenzyme Q2, polyprenyltransferase. | Isopentenyl-diphosphate Delta-isomerase 1; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.881 |
Coq2-2 | Lss | ENSMAUP00000013903 | ENSMAUP00000004363 | Coenzyme Q2, polyprenyltransferase. | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. | 0.774 |
Coq2-2 | Mvd | ENSMAUP00000013903 | ENSMAUP00000022730 | Coenzyme Q2, polyprenyltransferase. | Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. | 0.575 |
Coq2-2 | Rusc1 | ENSMAUP00000013903 | ENSMAUP00000018552 | Coenzyme Q2, polyprenyltransferase. | RUN and SH3 domain-containing protein 1 isoform X2. | 0.797 |
Coq2-2 | Sqle | ENSMAUP00000013903 | ENSMAUP00000003609 | Coenzyme Q2, polyprenyltransferase. | Squalene monooxygenase. | 0.824 |
Fdft1 | Coq2 | ENSMAUP00000022823 | ENSMAUP00000013272 | Squalene synthase. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.776 |
Fdft1 | Coq2-2 | ENSMAUP00000022823 | ENSMAUP00000013903 | Squalene synthase. | Coenzyme Q2, polyprenyltransferase. | 0.776 |
Fdft1 | Fdps | ENSMAUP00000022823 | ENSMAUP00000023841 | Squalene synthase. | Farnesyl pyrophosphate synthase-like. | 0.962 |
Fdft1 | Hmgcs1 | ENSMAUP00000022823 | ENSMAUP00000000028 | Squalene synthase. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.945 |
Fdft1 | Idi1 | ENSMAUP00000022823 | ENSMAUP00000018134 | Squalene synthase. | Isopentenyl-diphosphate Delta-isomerase 1; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.927 |
Fdft1 | LOC101826047 | ENSMAUP00000022823 | ENSMAUP00000014262 | Squalene synthase. | Lanosterol 14-alpha demethylase; Belongs to the cytochrome P450 family. | 0.998 |